It is well known that physical activity protects against cardiovascular disease, but exactly what are the factors that mediate this benefit? There are a number of candidates including changes in the way the body handles blood sugar, changes in cholesterol and other lipids, and changes in the amount and location of fat storage. Recently, investigators from Boston evaluated data from over 27,000 women in the Women’s Health Study. They calculated that changes in inflammation and hemostasis (blood clotting) were most closely associated with the beneficial effects of exercise on cardiovascular outcomes. While it has been recognized for some time that inflammation plays a role in cardiovascular disease, obesity, diabetes and other related chronic conditions these findings suggest it may be the dominant factor. Furthermore, sedentary living appears to be a pro-inflammatory condition, which is bad news for the cardiovascular system.
Friday, November 16, 2007
Sedentary Living is Inflammatory
It is well known that physical activity protects against cardiovascular disease, but exactly what are the factors that mediate this benefit? There are a number of candidates including changes in the way the body handles blood sugar, changes in cholesterol and other lipids, and changes in the amount and location of fat storage. Recently, investigators from Boston evaluated data from over 27,000 women in the Women’s Health Study. They calculated that changes in inflammation and hemostasis (blood clotting) were most closely associated with the beneficial effects of exercise on cardiovascular outcomes. While it has been recognized for some time that inflammation plays a role in cardiovascular disease, obesity, diabetes and other related chronic conditions these findings suggest it may be the dominant factor. Furthermore, sedentary living appears to be a pro-inflammatory condition, which is bad news for the cardiovascular system.
It is well known that physical activity protects against cardiovascular disease, but exactly what are the factors that mediate this benefit? There are a number of candidates including changes in the way the body handles blood sugar, changes in cholesterol and other lipids, and changes in the amount and location of fat storage. Recently, investigators from Boston evaluated data from over 27,000 women in the Women’s Health Study. They calculated that changes in inflammation and hemostasis (blood clotting) were most closely associated with the beneficial effects of exercise on cardiovascular outcomes. While it has been recognized for some time that inflammation plays a role in cardiovascular disease, obesity, diabetes and other related chronic conditions these findings suggest it may be the dominant factor. Furthermore, sedentary living appears to be a pro-inflammatory condition, which is bad news for the cardiovascular system.
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